This includes patients with ASIA impairment scales from A to D. This includes paraplegic and quadriplegic patients with complete or incomplete spinal cord injuries. Pediatric patients with any type of spinal cord injury as long as their spinal cords are continuous on MRI evaluation.Ability of child and caregiver to travel to Houston, Texas, and stay for at least 4 days, and to return for all Follow-up visits (patient is responsible for cost of travel and lodging while in Houston).Ability of child to understand and speak English.Survived at least six months with PSCI, but are less than 4 years post injury (± 30 days), and have fixed neurologic deficits related to their injury at the time of enrollment.Between 1 year and 15 years of age on the day of study BMPC infusion.The secondary objective is to determine if functional, physiological and anatomic outcome measures are improved after BMPC autologous transplantation in children with SCI. The primary objective of this study is to determine the safety of transplantation of the patient's own (autologous) Bone Marrow Progenitor Cells (BMPC) in children with SCI. Stem cells can be found throughout the body, but they are most common in the bone marrow, the thick, spongy material inside the bones. Stem cells are being studied a lot because of this ability and there is the possibility that they may be used to take the place of cells that are no longer working in different parts of the body because of disease (as in cancer, diabetes, and heart disease). Stem cells are "unspecialized" cells in the body that do not have a specific function yet (for example, they have not become "heart cells" or "brain cells" yet.) Stem cells are able to divide and develop into more mature, function-specific cells and take the place of those cells that die, are injured or can no longer function the way they are supposed to. Recent basic science and animal studies suggest that stem cell treatment can foster functional improvement after SCI by helping repair the primary injury and reducing the secondary injury. Because the current therapy does nothing to reverse the primary insult, significant advances in reducing the disability associated with SCI are unlikely. Current therapy is designed only to minimize the secondary events of SCI and other trauma-associated injuries. incomplete) and the spinal cord level of the injury. Outcome for SCI depends of the severity of the primary injury (complete vs. The injury is divided into the primary mechanical event which causes the injury, and the secondary events which follow. Of the estimated 11,000 cases of acute spinal cord injury (SCI) which occur each year in North America, 5% involve children. Why Should I Register and Submit Results?.To find clinical trials that are enrolling new participants, use the Search the Studies function on the NIH Clinical Center website.A Closer Look at Stem Cells, from the International Society for Stem Cell Research (ISSCR), is a website about stem cell science and research and includes handbooks and other resources for consumers, patients, and health care providers.More Videos! Click here to see all of our online videos. ![]() After watching, please complete our two-minute survey! ![]() Finally, she discusses how to recognize and avoid scams and how to decide about treatment for yourself or, if you are a health provider, how to counsel your patients.Ĭlick here to see Dr. She then summarizes what the research can tell us about how effective these treatments are for spinal cord injuries. She begins by clarifying what stem cells are and how they are used in different treatments. Fuhrman explains the complex and rapidly expanding field of stem cell medicine. SCI Forum Stem Cell Therapy for Traumatic Spinal Cord Injury Presented by Alicia Fuhrman, MD, Department of Rehabilitation Medicine, University of Washington, on Maat the University of Washington Medical Center
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